Antidepressants Uncovered
Antidepressants are often seen as lifesavers, yet their effectiveness is more limited than previously believed, with only about 30% of patients experiencing a full response. Concerns arise regarding the potential for antidepressants to lead to increased depression upon discontinuation. The simplistic notion of depression as a chemical imbalance is increasingly challenged, suggesting that the interactions between brain areas may play a more significant role.In this clip
From this podcast

Chasing Life
Treating the Depressed Brain
Related Questions
What causes depression? Most doctors say that it is not caused by a chemical imbalance in the brain. However, I find it strange that antidepressants allow us to use the serotonin produced in the brain for a longer period of time, and we start to feel bad when they are not there. Doesn't this mean that we cannot use serotonin sufficiently? Wouldn't not using serotonin well enough indicate a chemical imbalance? Can those who have knowledge on this subject enlighten me?
Is the idea that depression is a chemical imbalance and that it doesn't exist—since the brain always balances itself out—valid?