Balancing mTOR Activation
The discussion highlights the delicate balance between activating and inhibiting mTOR for optimal health and longevity. While mTOR activation is crucial for building muscle, which is essential for a long life, periods of inhibition are necessary for cellular cleanup through autophagy. It’s important to incorporate fasting and protein strategically to achieve this balance, rather than adhering strictly to a vegan or vegetarian diet.In this clip
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Related Questions
I'm concerned about the role of mTOR and IGF-1 in tumor growth as discussed in episode 313: What science still gets wrong about longevity | Robb Wolf, biochemist & New York Times bestselling author, and the clip Fasting and mTOR. Is there a balance that can be achieved between activating these pathways for muscle growth and strength training, and downregulating them through fasting? For example, could a cycle of 1 month of muscle-building weight training followed by a week of fasting help strike that balance? What might an optimal approach look like?
Is it more beneficial to eat a high-protein diet as we get older or to reduce protein to slow the mTOR response, based on the episodes How To SLOW & REVERSE The Aging Process For LONGEVITY | Dr. Mark Hyman, Shocking Truth About Protein & Why You Need To Eat More For Longevity | Dr. Mark Hyman, and Protein, fasting, cancer, and longevity | Valter Longo, PhD, as well as the clips Unlocking Autophagy and Protein Intake Impact?