Maintaining a healthy gut microbiome is crucial for regulating estrogen levels, as an imbalance can lead to the reactivation of estrogen in the body. A low-fiber diet can exacerbate this issue, highlighting the need for daily bowel movements to effectively detoxify estrogen. Additionally, calcium d-glucarate can serve as a protective nutrient for those experiencing symptoms of estrogen dominance, emphasizing the interconnectedness of gut health and hormonal balance.