403: Simple Ways to Boost Nitric Oxide for Better Heart, Brain, and Immune Function | Nathan Bryan, PhD

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Health Risks
Antacid medications, particularly proton pump inhibitors (PPIs), pose significant health risks by inhibiting nitric oxide production. explains that these drugs disrupt the body's ability to regulate blood flow, leading to increased inflammation and oxidative stress, which are precursors to chronic diseases like heart attacks and strokes 1. He highlights the paradox of insufficient stomach acid production being a root cause of gastroesophageal reflux, which these medications aim to treat 2.
Without stomach acid, we can't break down proteins into amino acids, leading to food allergies and autoimmunity.
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This disruption in digestion can lead to nutrient deficiencies and further health complications.
Dependency Issues
The widespread use of PPIs has led to a dependency dilemma, with millions relying on these drugs despite their risks. notes that PPIs were the first billion-dollar drug, with over 200 million prescriptions annually, contributing to nutrient deficiencies and chronic illness 3. He criticizes the lack of long-term safety data, comparing it to other industrial chemicals that have been allowed on the market without thorough testing 4.
If I wanted to make you chronically ill and dependent upon drug therapy for the rest of your life, I'd give you a proton pump inhibitor.
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This dependency is exacerbated by misleading safety data, which often emerges at the expense of consumers.