Is L-Arginine the key to Stronger and Longer Lasting Erections?
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Episode Highlights
Scientific Evidence
Dr. discusses the role of L-Arginine and L-Citrulline as nitric oxide boosters, which are crucial for improving erectile function. She highlights a meta-analysis of ten randomized controlled trials showing that daily doses of 2.8 to 8 grams of L-Arginine significantly improved erectile function in men with mild to moderate erectile dysfunction 1. In a more recent study, high doses of L-Arginine taken over three months also showed significant improvements in erectile function and blood flow 1.
L-Arginine increases the availability of nitric oxide and cgmp, leading to improved erectile function and increased blood flow.
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She notes that men with cardiovascular diseases or diabetes may benefit the most from these supplements, though caution is advised for those with allergies or asthma 1.
Bioavailability
The bioavailability of L-Arginine is a significant concern, as it requires multiple doses throughout the day due to rapid breakdown in the body. Dr. Malik explains that L-Citrulline, which is converted into L-Arginine in the kidneys, offers a more sustained release and better bioavailability 2. This makes L-Citrulline a more practical option for increasing blood levels of L-Arginine and improving erectile function.
Oral citrulline is better than oral arginine at increasing blood levels of arginine itself.
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She also mentions that L-Citrulline may encourage the release of vascular endothelial growth factor, which improves blood vessel function in the penis 2.