107 - Osteoporosis: What is it and how to prevent it, with Prof James Simon

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Osteoporosis Basics
and discuss osteoporosis, emphasizing its silent yet severe nature. Osteoporosis is a condition where bones become weak and brittle, often unnoticed until a fracture occurs. highlights the critical role of calcium metabolism in maintaining bone health, noting that the skeleton acts as a reservoir for calcium, essential for various bodily functions 1. He explains that bone density, measured through devices like Dexa scans, accounts for about 60% of bone strength, with the remaining 40% influenced by other factors 2.
The skeleton is actually a very active tissue in the human body. Even though it's on the inside of us, we don't get to see it, but it's very metabolically active.
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Understanding these basics is crucial for recognizing the importance of maintaining bone health, especially in postmenopausal women who are at higher risk 3.
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Risk Factors
The risk factors for osteoporosis are multifaceted, involving hormonal, racial, and genetic elements. explains that postmenopausal women are particularly vulnerable due to decreased estrogen levels, which are crucial for bone maintenance 3. Additionally, individuals with a family history of osteoporosis or those on certain medications, like glucocorticoids, face increased risks 4.
Depression is actually a big problem for women and for postmenopausal women and women as they age, and many of the antidepressants at a yet another risk factor for osteoporosis and fracture.
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Understanding these risk factors is essential for early intervention and prevention, as osteoporosis often remains undetected until a fracture occurs 1.
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Long-term Impact
Osteoporosis has significant long-term impacts on life expectancy and quality of life. notes that fractures, particularly hip fractures, can drastically reduce mobility and independence, often leading to a decline in overall health 5. He emphasizes the importance of early detection and prevention, suggesting regular bone density tests to monitor bone health 6.
Most fractures, whether they're the hip or a spine type fracture, most fractures are preventable. So if it's going to kill you early and it's preventable, why wouldn't you do it?
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Preventative measures, including adequate calcium and vitamin D intake, along with weight-bearing exercises, are crucial in mitigating these risks 1.