Curcumin may play a dual role in cancer prevention by modifying thyroidoxin reductase, shifting its function from antioxidant to pro-oxidant. While it can induce programmed cell death in cancer cells, it does not differentiate between healthy and cancerous cells, raising concerns about its safety. Dosing studies indicate potential adverse effects such as nausea and diarrhea, challenging the perception of curcumin as a harmless supplement.
