Insulin Resistance Explained

A deep dive into the complexities of insulin resistance reveals the critical difference between physiological and pathological states. Low carbohydrate, high fat diets can lead to a glucose-sparing effect, where muscles prioritize free fatty acids over glucose. In contrast, excessive calorie intake from mixed carbohydrates and fats can cause adipocytes to become insulin resistant, leading to high insulin and glucose levels, a hallmark of type 2 diabetes. Understanding these mechanisms is vital for addressing metabolic health.