Protein and Exercise
Simon and Joel discuss the effects of protein and exercise on IGF-1 levels, highlighting how exercise influences IGF-1 differently than protein intake. They delve into the importance of tissue specificity in IGF-1 activation and its implications for muscle growth and longevity.In this clip
From this podcast

The Proof with Simon Hill
Achieving Longevity and Healing through Food: A Deep Dive | Dr. Joel Fuhrman, Md
Related Questions
How does exercise influence IGF-1 levels in relation to the episode Protein, fasting, cancer, and longevity | Valter Longo, PhD and the clip Protein Intake Insights?
I have a question about the episode Dr Layne Norton: The Science of Eating for Health, Fat Loss & Lean Muscle | Huberman Lab Podcast #97 and the clip Protein and Longevity. I'm concerned about the role of mTOR and IGF-1 in tumor growth as discussed in episode 36 of the Huberman Lab Podcast. Is there a balance that can be achieved between activating these pathways for muscle growth and strength training, and downregulating them through fasting? For example, could a cycle of 1 month of muscle-building weight training followed by a week of fasting help strike that balance? What might an optimal approach look like?
I have a question about the episode Dr Layne Norton: The Science of Eating for Health, Fat Loss & Lean Muscle | Huberman Lab Podcast #97 and the clip Protein and Longevity. I'm concerned about the role of mTOR and IGF-1 in tumor growth as discussed in episode 313: What science still gets wrong about longevity | Robb Wolf, biochemist & New York Times bestselling author, and the clip Fasting and mTOR. Is there a balance that can be achieved between activating these pathways for muscle growth and strength training, and downregulating them through fasting? For example, could a cycle of 1 month of muscle-building weight training followed by a week of fasting help strike that balance? What might an optimal approach look like?