Dopamine and Opioids
Robert discusses the contrasting mechanisms of dopamine release between stimulants and opioids, highlighting how opioids indirectly enhance dopamine neuron activity. He shares personal experiences with pain relief medications, noting the varying subjective effects of opioids, which can range from euphoria to sedation. The conversation delves into the historical significance of opioids, illustrating their powerful impact on society and individual experiences.In this clip
From this podcast

Huberman Lab
Dr. Robert Malenka: How Your Brain’s Reward Circuits Drive Your Choices | Huberman Lab Podcast
Related Questions
How do opioids work in the brain?
How do opiates affect brain receptors as discussed in the episode Dr. Robert Malenka: How Your Brain’s Reward Circuits Drive Your Choices | Huberman Lab Podcast and the clip Dopamine and Opioids?
How do opiates affect brain receptors in the episode Dr. Robert Malenka: How Your Brain’s Reward Circuits Drive Your Choices | Huberman Lab Podcast and the clip Dopamine and Opioids?