Psychedelics and Autism

The conversation delves into the potential of psychedelics to enhance metaplasticity, particularly in relation to autism and fragile X syndrome. There’s a discussion about the role of metabotropic glutamate receptors and the hypothesis that autism may stem from a failure to close critical developmental periods. While the idea of combining psychedelics with specific modulators is intriguing, caution is advised regarding human trials without prior safety testing in animal models.