Various antipsychotics, such as aripiprazole and haloperidol, show comparable efficacy in treating delirium, with aripiprazole being favored for its minimal QTc prolongation. Dexmedetomidine presents a useful option for sedation in ICU settings, particularly for patients with respiratory complications. Emerging research highlights melatonin's potential as an adjunct treatment, showcasing its ability to modulate immune responses and reduce mortality in infected models.
