Leptin plays a crucial role in signaling satiety and fat burning, but leptin resistance can lead to headaches and sleep disturbances. Sleep is essential for activating the glymphatic system, which detoxifies the brain by breaking down harmful proteins like beta amyloid, linked to neurodegenerative diseases. Melatonin emerges as a powerful antioxidant, aiding in the removal of neurotoxins and reducing brain inflammation.
