Adenosine and Caffeine

Adenosine plays a crucial role in regulating our sleepiness and fatigue levels, accumulating the longer we are awake. Caffeine, consumed by over 90% of adults, temporarily blocks adenosine receptors, preventing feelings of sleepiness but leading to a subsequent energy crash as adenosine builds up. Understanding the interplay between adenosine and sleep can shed light on why we feel fatigued and how our bodies reset during rest.