Heat and Opioid Receptors

Rhonda and Charles discuss the relationship between heat stress, endorphins, and opioid receptors. Rhonda shares her personal experience with increased endorphins from heat exposure and explores the possibility of sensitizing mu opioid receptors. Charles talks about the opposite effect of kappa opioid receptors and the potential for a novel antidepressant. They also touch on the similarities between heat stress and exercise in their effects on the inflammatory pathway.