LPA and Atherosclerosis

Benoît explains how LPA is a main driver before the onset of any discernible plaque, but it also has a double whammy where it initiates the disease and is associated with the progression of the disease. LPA is associated with inflammation, with the inflammatory plaque, even in patients that don't have established disease. It is also strongly associated with aortic stenosis, peripheral artery disease, ischemic cerebral strokes, and kidney disease.