Matthew discusses the specific risks associated with classic psychedelics, particularly for individuals with psychotic predispositions. He highlights the importance of structured screenings to identify at-risk populations and notes that while there are some side effects, such as headaches and a slight increase in blood pressure, serious long-term effects are rare. The conversation also touches on the phenomenon of hallucinogen persisting perceptual disorder, emphasizing its connection to recreational use rather than clinical settings.
