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Melatonin and Inflammation

Melatonin exhibits both immune-stimulating and immune-dampening effects, depending on the context of inflammation. Research shows that melatonin can reduce proinflammatory cytokines and improve outcomes in conditions like respiratory distress syndrome and chronic inflammation. Additionally, it plays a role in modulating the NLRP3 inflammasome, which is crucial in various inflammatory disorders. Its benefits extend beyond inflammation, as melatonin also enhances sleep quality, further supporting immune function.