Gut Microbiome Mismatch

The gut microbiome exhibits remarkable adaptability, changing rapidly in response to dietary shifts, unlike the slower evolution of human genetics. Over the past 75 years, significant changes in food production, lifestyle, and environmental factors have led to a decrease in microbial diversity, creating a mismatch with our traditional human biology. This discord triggers a low-grade chronic immune response, contributing to the rise of chronic diseases despite longer lifespans.