Growth vs. Repair
A delicate balance exists between mTOR activation and autophagy, both crucial for cellular health. While mTOR promotes growth, excessive activation can lead to unwanted cell proliferation, whereas autophagy facilitates repair but can lead to muscle loss if overemphasized. Embracing a feast-famine cycle through intermittent fasting and adequate protein intake can optimize both pathways, promoting longevity and overall well-being.In this clip
From this podcast
Dr. Jockers Functional Nutrition
Fasting, Hormetic Stress, Protein, mTOR, and Longevity with Ben Azadi
Related Questions
I'm concerned about the role of mTOR and IGF-1 in tumor growth as discussed in episode 313: What science still gets wrong about longevity | Robb Wolf, biochemist & New York Times bestselling author, and the clip Fasting and mTOR. Is there a balance that can be achieved between activating these pathways for muscle growth and strength training, and downregulating them through fasting? For example, could a cycle of 1 month of muscle-building weight training followed by a week of fasting help strike that balance? What might an optimal approach look like?
I'm concerned about the role of mTOR and IGF-1 in tumor growth as discussed in the episode 313: What science still gets wrong about longevity | Robb Wolf, biochemist & New York Times bestselling author and the clip Fasting and mTOR. Is there a balance that can be achieved between activating these pathways for muscle growth and strength training and downregulating them through fasting? For example, could a cycle of 1 month of muscle-building weight training followed by a week of fasting help strike that balance? What might an optimal approach look like?
I'm concerned about the role of mTOR and IGF-1 in tumor growth as discussed in the episode How To Build Muscle, Lose Weight & Stay Young For LONGEVITY | Donald Layman and the clip mTOR and Aging. Can we achieve a balance between activating these pathways for muscle growth and strength training, and downregulating them through fasting, as mentioned in the episode Dr. David Sinclair: The Biology of Slowing & Reversing Aging | Huberman Lab Podcast #52 and the clip Leucine and Longevity? For example, could a cycle of 1 month of muscle-building weight training followed by a week of fasting help strike that balance? What might an optimal approach look like?