High levels of oxidative stress can lead to the oxidation of LDL cholesterol, which is influenced by its particle size. Larger, buoyant LDL particles are protected by fat-soluble antioxidants, while small, dense LDL particles are more vulnerable and can penetrate the endothelial lining, leading to potential health issues. Maintaining low insulin levels is crucial to preventing the formation of these harmful small LDL particles.
