Inflammation and Genetics
Yael discusses how the ApoE gene, particularly the ApoE4 variant, has evolved from a beneficial trait in our hunter-gatherer ancestors to a potential risk factor for modern diseases due to chronic inflammation. She emphasizes that genetic variations should not be labeled as mutations, as their impact is largely influenced by environmental factors, diet, and lifestyle choices. David adds that the hyper-responsive inflammatory system was once crucial for survival against infections, but in today's world, it can lead to health issues instead.In this clip
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