Absolutely, exercise can significantly aid in weight loss. It's important to consider the intensity of the exercise and how it interacts with our fat stores. High intensity movements, especially when performed in a fasted state, can be particularly useful for fat oxidation. However, if you're planning on a long duration exercise, whether you eat or not probably doesn't matter unless you're exercising for longer than 90 minutes. So, in essence, the type of exercise, its intensity, and the timing of your meals can all play a role in how effectively exercise can help with weight loss.