Published Jul 19, 2024

Simple Steps to Boost Your Daily Energy with NAD | 1182 | Dave Asprey

Discover the revolutionary benefits of NAD supplements with Dr. Nichola Conlon as she and Dave Asprey explore how innovative delivery methods and lifestyle changes can rejuvenate energy, combat aging, and improve health by addressing NAD decline and inflammation.
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  • NAD Basics

    NAD, a vital molecule present in every cell, plays a crucial role in energy production and cellular repair. Dr. Nichola Conlon explains that NAD is integral to the Krebs cycle, converting glucose into ATP, the energy currency of cells 1. Without NAD, cellular respiration would cease, leading to immediate death. Additionally, NAD fuels repair enzymes that fix cellular damage, such as DNA and protein damage 1. highlights the importance of maintaining high NAD levels for energy and repair efficiency 2.

       

    Decline with Aging

    As we age, NAD levels decline significantly, impacting cellular energy and contributing to aging symptoms. Dr. Conlon notes that NAD levels halve every 20 years, starting from birth, leading to fatigue and cellular damage 2. This decline is linked to the aging process, affecting mitochondrial function and hormone production. Asprey3.

       

    NAD Production

    NAD production involves complex pathways that change with age, affecting its availability. Dr. Conlon explains that precursors like NMN are used to boost NAD, but their effectiveness diminishes as the enzymes needed for conversion decline with age 4. She uses a factory analogy to illustrate that without functioning machinery, adding more raw materials won't increase production. Additionally, natural molecules like quercetin can enhance NAD production by activating specific enzymes, highlighting the importance of bioavailability in supplementation 5.

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