Thermogenesis and Obesity
Manolis discusses the intricate relationship between thermogenesis and obesity, highlighting how specific genetic mutations can hinder the body's ability to burn calories as heat. This understanding opens the door to potential interventions using advanced technologies like CRISPR, enabling the manipulation of fat cells to switch between energy-storing and energy-burning states. The conversation emphasizes the groundbreaking discoveries made since 2007, which have reshaped our understanding of obesity at a molecular level.In this clip
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Lex Fridman Podcast
Manolis Kellis: Biology of Disease | Lex Fridman Podcast #133
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