Evolution and Immunity
The human genome showcases fascinating adaptations, where immune genes have taken on non-immune roles, such as microglia pruning unused neuronal connections. Genetic variations influence susceptibility to diseases like COVID-19, revealing how our evolutionary past shapes current health outcomes. The discussion highlights the ruthless nature of natural selection, where traits that promote survival, even if not inherently "better," persist in the gene pool, as seen in the rising prevalence of obesity-related genes in different populations.In this clip
From this podcast

Lex Fridman Podcast
Manolis Kellis: Human Genome and Evolutionary Dynamics | Lex Fridman Podcast #113
Related Questions
Is my brain limited by genetic factors in terms of how able it is to utilize my neurological abilities as discussed in the episode Manolis Kellis: Biology of Disease | Lex Fridman Podcast #133 and the clip Human Uniqueness Explored?
Is my brain limited by genetic factors in terms of how able it is to utilize my neurological abilities, as discussed in the episode Manolis Kellis: Biology of Disease | Lex Fridman Podcast #133 and the clip Human Uniqueness Explored?