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Metabolism and Microbiome

The ability to burn calories is influenced by genetic factors, particularly the FTO locus and its target genes, which determine whether fat cells become fat burning or storing. Surprisingly, personalized nutritional advice is more closely tied to the gut microbiome than to one's genetic makeup. The interplay between gut bacteria, genetics, and environment creates a complex landscape for nutrition, highlighting the body's remarkable adaptability to different dietary practices, such as fasting.