mTOR Balance Explained
The conversation highlights the critical balance between mTOR and AMPK in the context of aging and muscle maintenance. While mTOR is often vilified, it's essential for muscle growth and recovery, especially as we age. Cycling between inhibiting and stimulating mTOR, much like fasting and refeeding, is vital for maintaining overall health and preventing frailty.In this clip
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LONGEVITY with Nathalie Niddam
Unlocking Lifelong Vitality with Dr. Elizabeth Yurth: Myths, Medicine & Longevity | Ep #241
Related Questions
I'm concerned about the role of mTOR and IGF-1 in tumor growth as discussed in episode 313: What science still gets wrong about longevity | Robb Wolf, biochemist & New York Times bestselling author, and the clip Fasting and mTOR. Is there a balance that can be achieved between activating these pathways for muscle growth and strength training, and downregulating them through fasting? For example, could a cycle of 1 month of muscle-building weight training followed by a week of fasting help strike that balance? What might an optimal approach look like?
I'm concerned about the role of mTOR and IGF-1 in tumor growth as discussed in episode 36. AMA#2: Acid/base balance, APOE4/FTO, omega-3s, carnivore diet types, the problem with broccoli and more! and the clip Ketosis, mTOR, IGF-1. Is there a balance that can be achieved between activating these pathways for muscle growth and strength training and downregulating them through fasting? For example, could a cycle of 1 month of muscle-building weight training followed by a week of fasting help strike that balance? What might an optimal approach look like?
I'm concerned about the role of mTOR and IGF-1 in tumor growth as discussed in the episode How To Build Muscle, Lose Weight & Stay Young For LONGEVITY | Donald Layman and the clip mTOR and Aging. Can we achieve a balance between activating these pathways for muscle growth and strength training, and downregulating them through fasting, as mentioned in the episode Dr. David Sinclair: The Biology of Slowing & Reversing Aging | Huberman Lab Podcast #52 and the clip Leucine and Longevity? For example, could a cycle of 1 month of muscle-building weight training followed by a week of fasting help strike that balance? What might an optimal approach look like?