Kidney

Andrew Huberman discusses the importance of understanding kidney function, especially in relation to hydration and circadian rhythms. He mentions that kidney function is optimal during the first 10 hours after waking due to circadian rhythms, making this time critical for hydration. The kidneys regulate fluid balance in the body by filtering out contaminants and adjusting hormone levels, especially antidiuretic hormone (vasopressin), which influences whether the body retains or excretes fluid based on several factors including salt concentration and fluid needs 1.

For a more detailed exploration of kidney health and the impacts of conditions like high blood pressure, Peter Attia highlights the kidney's sensitivity to high blood pressure and how this can affect long-term health. He emphasizes the need for accurate measures of kidney function and discusses how kidney health is often overlooked in medical assessments 2.