Can caffeine help with hair loss?

Caffeine can indeed help with hair loss when used topically. Topical application of caffeine works by suppressing PDE and indirectly stimulating IGF One, which can increase hair growth or at least maintain it in a treated area. It has been noted that topical caffeine can be as effective as minoxidil without negative side effects like lowering blood pressure or increasing prolactin. However, drinking more caffeine won't help offset hair loss; it needs to be applied to the scalp as an ointment or cream about three times a week. The exact concentration varies greatly among different products, and regular use is essential for noticeable effects 1.