BPC 157
Sources:
BPC 157 is a peptide that has gained attention for its potential in recovery and repair. Benefits discussed on the Mind Pump Podcast include:
- It upregulates growth hormone receptors, which makes any growth hormone in the body more effective 1.
- It works well for repair of injuries if used site-specifically and has a systemic effect even when taken orally 2.
- BPC 157 is known for improving the gut barrier, enhancing cell adhesion, and indirectly improving the microbiome 3.
- Some people reported rapid healing effects anecdotally 4.
- There are animal studies suggesting its effectiveness for repairing tendons, joints, skin, and its uses for IBD and IBS 5.
Dr. William Seeds noted that BPC enhances what you're doing with growth hormone releasing peptides because it upregulates growth hormone receptors on cells. This could lead to improved efficiencies in the cell 1. He also prefers site-specific injections for injury repair, asserting that they work better than systemic injections for this purpose 2. Oral BPC is more beneficial for gut health due to its effects on cell adhesion and barrier function, suggesting it could improve the production of natural antimicrobials 3. Dr. Seeds also would consider BPC 157 as a beneficial addition even for younger individuals, especially for gastrointestinal health, and would take it orally at lower doses for its potential benefits to the microbiome 6.
In terms of safety and usage, it has been advised to obtain peptides like BPC 157 through a physician and pharmacy rather than grey-market sources to ensure quality and avoid counterfeit products 7.
Overall, while there appear to be many anecdotal reports and some animal studies that suggest the effectiveness of BPC 157, the lack of extensive human clinical trials was also highlighted 5. There is an emphasis on individual variance, with some people noticing significant effects while others may not feel any difference. Careful and informed use, under the guidance of a healthcare professional, seems advisable 7.
RELATED QUESTIONS