How much glutamine is optimal?

Andrew Huberman discusses glutamine supplementation in various contexts. Generally, people supplement with glutamine by taking anywhere from 1 gram to as much as 10 grams per day 1. Huberman himself takes higher dosages several times throughout the day when feeling particularly run down 2.

He notes that a teaspoon (roughly equivalent to about 5 grams) taken multiple times a day can help reduce sugar cravings 3. However, he advises easing into higher dosages gradually to avoid potential gastric distress 4. If you are considering glutamine supplementation, it is always best to consult a healthcare professional, especially if there are any health concerns like a predisposition to cancer, as glutamine can fuel certain types of tumors 5.