Why shouldn’t you take ibuprofen with alcohol?

Mixing ibuprofen with alcohol is not recommended due to several health risks. According to experts, taking ibuprofen with alcohol can increase the potential for liver toxicity and slow down alcohol metabolism, which could exacerbate its effects 1. It's emphasized that combining ibuprofen with alcohol can increase the risk of gastrointestinal bleeding or damage due to the irritant effects of alcohol on the stomach lining, which are amplified by NSAIDs like ibuprofen 2. Therefore, it's important to avoid taking ibuprofen while consuming alcohol to mitigate these risks.