• HCG as an alternative to TRT?

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    Human Chorionic Gonadotropin (HCG) is sometimes used as an alternative to Testosterone Replacement Therapy (TRT). Dr. Kyle Gillett mentioned during a discussion with that HCG can be used in monotherapy, and some people are on HCG alone. It can be marginally better for lipids than being on TRT. Some clinics advertise HCG as a non-suppressive alternative to TRT; however, it is suppressive of Luteinizing Hormone (LH) and can increase estrogen levels. HCG can also improve the sensitivity of the genitals and is used as a treatment for conditions like post-finasteride syndrome by upregulating dihydrotestosterone (DHT). It must be noted, though, that upon discontinuation of HCG, a strategy to return to normal hormone levels as fast as possible is necessary 1.

    Use of testosterone from an external source, like TRT, can dramatically reduce sperm count. HCG, being a mimic for LH, can stimulate the testes to continue to make testosterone and indirectly support spermatogenesis. It's pivotal to have a conversation with a healthcare provider about these effects, especially if there is a desire to conceive children in the future 2.

    For maintaining testicular function and possibly for fertility, HCG has been discussed as an adjunct treatment alongside or in place of TRT, depending on the specific needs and health condition of the individual 3.

    Men considering HCG as an alternative to TRT should consult with a healthcare provider to fully discuss the benefits, risks, and their specific health goals.

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