How much fibre is the daily recommended dose for optimal gut health?

For optimal gut health, the recommended daily intake of fiber is at least 35 grams per day for men and 25 grams per day for women 1. However, it's important to note that most individuals consume significantly less than these amounts.

There is currently no expert data available addressing the specific question of whether women go into autophagy faster during the late luteal phase of their menstrual cycle. Further research or consultation with a healthcare professional might provide more insights on this topic.

Hormones significantly influence autophagy, particularly the sex hormones. According to Dr. Mindy Pelz, the hypothalamus and pituitary gland, which are crucial for hormonal regulation, do not have a blood-brain barrier, making them highly sensitive to toxins. These toxins can disrupt hormonal balance, as seen in conditions like polycystic ovarian syndrome, which is linked to imbalances in testosterone and estrogen. Autophagy assists in repairing these brain regions, thus supporting better hormonal control.

Additionally, the cells surrounding the testes and ovaries, which release sex hormones, respond well to autophagy. When in a state of autophagy, these cells improve their function and effectively produce hormones. This interaction suggests a potential benefit of autophagy in managing hormonal health and could be a factor in addressing broader issues like the decline in testosterone and libido observed in modern populations 1.

Autophagy plays a crucial role in influencing hormonal regulation, particularly concerning sex hormones. As explained by Dr. Mindy Pelz, autophagy can repair key parts of the brain like the hypothalamus and pituitary, which control hormonal activities. These brain parts are particularly vulnerable to toxins due to their lack of a blood-brain barrier. When autophagy is active, it can initiate repairs and improve the performance of these areas, preventing hormonal imbalances such as those seen in conditions like polycystic ovarian syndrome.

Furthermore, autophagy influences the cells surrounding the testes and ovaries, which are responsible for the production of sex hormones. When these cells engage in autophagy, their functionality improves, leading to better production and regulation of sex hormones. This effect of autophagy suggests a potential approach to addressing issues linked to the macro decline in male testosterone and libido commonly discussed today 1.

A 0.2 mmol increase in blood sugar does not typically break a fast. Andrew Huberman explains that the breaking of fast primarily depends on whether something you ingest significantly increases your resting blood glucose and for how long. For most people, including himself, ingesting substances that do not contain substantial amounts of carbohydrates or sugars is unlikely to break a fast, proving that a slight elevation in blood glucose by 0.2 mmol is unlikely to constitute a break in your fast 1.