Does melatonin affect sexual health?

Melatonin can impact sexual health due to its influence on hormone levels. Dr. Andrew Huberman expressed concerns that melatonin supplementation, particularly at high doses, can affect the body's hormonal balance. Melatonin is known to suppress the onset of puberty and interacts with other hormones, including testosterone and estrogen. Since these hormones are critical for sexual health and libido in both men and women, altering their natural levels with melatonin supplements could lead to significant sexual side effects. Therefore, Huberman advises against regular melatonin use and suggests reserving it for occasional situations like jet lag 1 1.