Does vaping impact testosterone levels?

Vaping does impact testosterone levels. Specifically, nicotine, which is commonly consumed through vaping, can negatively affect both testosterone and estrogen levels. The concern with nicotine, whether from tobacco or other sources, is its dose-dependent impact on hormone profiles, along with the risk of cardiovascular disease associated with its vasoconstrictive properties. Therefore, even when consumed in different forms like nicotine gum, if the dose is high, it can still be detrimental to hormonal health over a long period 1.