Should you rely on melatonin for sleep?

Relying on melatonin for sleep may not be advisable. According to Andrew Huberman on the Knowledge Project, the typical dosages found in melatonin supplements are much higher than what your body naturally produces. This can interact with other hormone systems in potentially harmful ways. For example, melatonin can suppress the onset of puberty and interfere with testosterone and estrogen, which are critical for various bodily functions 1.

Huberman particularly emphasizes that melatonin should not be used regularly but might be sparingly utilized for situations like jet lag. Over-reliance on this powerful hormone can lead to unwanted side effects, hence it's better to adopt other sleep-friendly habits 1.