Can omega-3 help bipolar disorder?

Omega-3 fatty acids can be beneficial in managing some symptoms of bipolar disorder. Andrew Huberman discusses a study published in the American Journal of Psychiatry, which shows that omega-3 supplementation led to changes in neuroplasticity and brain cell membrane fluidity in individuals with bipolar disorder, bringing their neural circuits closer to those found in healthy individuals 1.

Another study highlighted by Andrew Huberman involved high-dose fish oil supplementation (9.6 grams per day for four months), which significantly reduced symptoms of bipolar depression compared to a control group 2. However, he cautions that omega-3 should not be viewed as a sole treatment but as a supplementary approach, alongside traditional prescription medications and talk therapy, due to the complexity and severity of the disorder 3.