Are oral NAD supplements beneficial?

Andrew Huberman discussed the effectiveness of oral NAD supplements on the Huberman Lab. He noted that while there are products claiming to deliver NAD orally, he is not aware of any studies directly linking oral NAD to increased NAD levels in cells. He emphasized that more scientific research is required to validate these claims 1.

Given the current lack of evidence, it's unclear if oral NAD supplements can effectively raise cellular NAD levels. He personally prefers NAD infusions for their noticeable benefits, although they are expensive and uncomfortable 2. Overall, emphasis should be placed on foundational health practices like proper light exposure, movement, and nutrition before considering supplementation 1.

Further validation from experts like Dr. David Sinclair indicates a preference for NAD precursors like NMN, which has been shown to double NAD levels in the blood during clinical trials 3.