• What are serotonin supplements?

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    Serotonin supplements are used to increase serotonin levels in the brain, which can influence feelings of well-being and happiness. These supplements usually contain precursors to serotonin, such as 5-HTP or tryptophan.

    • 5-HTP and Tryptophan: These are precursors to serotonin and can be taken to potentially enhance levels of this neurotransmitter. However, Dr. Huberman has reservations about using these regularly due to potential disruptions in sleep architecture. He suggests that individual responses can vary, and it's important to consult a healthcare provider before starting these supplements 1.

    • Myo-Inositol: This supplement has also been discussed by Dr. Huberman for its potential to increase serotonin levels. He noted improvements in his own sleep quality when using it, although high dosages are often associated with gastrointestinal discomfort 2.

    • Cissus Quadrangularis: Another supplement mentioned by Dr. Huberman, known to increase serotonin levels and potentially aid in weight control because of its impact on appetite 3.

    • Kanna (Sceletium tortuosum): This herb, also known as Zembrin, is another over-the-counter compound that can enhance serotonin levels and promote states of comfort and pleasure, making it useful for enhancing gratitude practices 4.

    Despite the potential benefits, Dr. Huberman emphasizes caution when using these supplements due to possible side effects, such as alterations in sleep patterns, appetite, and libido, and highlights the importance of individual response to such treatments.

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