Artificial vs. non-caloric sweeteners?


Artificial sweeteners, compared to non-caloric sweeteners, engage differently with our taste and metabolic systems. Initially, artificial and non-caloric sweeteners aren't preferred due to their effect on sweetness perception without increasing dopamine levels, as they don't raise blood glucose levels. Over time, however, with repeated consumption, dopamine levels can rise, leading to increased consumption and eventual pleasure from these sweeteners. This can condition users to seek them out more frequently 1.

Furthermore, it's crucial to consider how and when artificial sweeteners are consumed. Consuming them with food that increases blood glucose can lead to increased insulin secretion, even when later consumed alone. This linkage can disrupt insulin and glucose management and is a key factor in how artificial sweeteners impact metabolic health 1 2.

In summary, while artificial sweeteners can help reduce calorie intake, their consumption patterns, and pairing with other food can significantly affect metabolic responses. Caution is advised, especially regarding pairing with high-glucose foods to avoid negative metabolic consequences 2.

Artificial Sweeteners

Andrew explains how artificial sweeteners interact with our taste system and affect our dopamine levels and blood glucose. He discusses how we can rewire our taste system and the effects of consuming artificial sweeteners over time.

Huberman Lab

Nutrients For Brain Health & Performance | Huberman Lab Podcast #42