What is androgen receptor density?

Androgen receptor density refers to the number of androgen receptors available in the body. These receptors are crucial since they are what testosterone and other androgens bind to in order to exert their effects, such as promoting muscle growth and strength.

The Mind Pump team discusses how the effectiveness of testosterone in building muscle is not just about the quantity of testosterone but also about the density of androgen receptors. Higher density means more receptors for testosterone to bind to, leading to better muscle-building outcomes. This concept is highlighted in a study they reference, which found that androgen receptor density was a better predictor of strength and muscle gains compared to testosterone levels alone 1 2.

Strength training is noted as a reliable method to increase androgen receptor density, which in turn enhances the body's ability to utilize testosterone effectively 3. Therefore, even if a person has lower testosterone levels, higher androgen receptor density can help them achieve comparable or better muscle growth than someone with higher testosterone but lower receptor density 4.