What are longevity drugs?
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Longevity drugs are pharmaceutical compounds aimed at extending lifespan and improving overall health during aging. Here are some insights from trusted experts on this topic:
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Metformin: Commonly used for diabetes, metformin has potential longevity benefits. notes that although direct human studies are lacking, the drug shows promise in reversing aspects of the aging process based on the nine hallmarks of aging 1.
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Rapamycin: This drug is highlighted for its ability to extend lifespan significantly, even when administered in older animals. considers it a groundbreaking drug for its role in inhibiting the mTOR pathway, crucial for nutrient sensing and longevity 2.
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NMN and NAD-related Compounds: These drugs are designed to target aging directly by acting on cellular metabolism. emphasizes their potential to revolutionize age-related therapy by not just targeting specific diseases but aging itself 3.
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Acarbose and Low-Dose Naltrexone: mentions the repurposing of drugs such as acarbose (used for diabetes) and low-dose naltrexone (originally for addiction) for their potential longevity benefits. These drugs may help manage glucose levels and chronic diseases when used in low doses 4.
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Upcoming Treatments: There is ongoing research on developing new longevity drugs that treat aging as a disease rather than addressing individual age-related conditions. This concept includes drugs that may work across multiple pathways to delay the aging process and improve health span 5.
These insights underline the innovative efforts in the field of longevity research, seeking to achieve healthier and longer lives through pharmaceutical intervention.
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