What are psilocybin dosages?

In clinical trials involving psilocybin, the dosages commonly used are as follows:

• Microdosing: Typically, this involves very small and sub-perceptible doses. However, precise microdose amounts in terms of milligrams of psilocybin are more complex to define due to variations in mushroom potency and consumption forms.

• Macro or Standard Doses:

  • 10 mg of psilocybin: Used in clinical trials for psychological therapy.
  • 25 mg of psilocybin: Often used in controlled studies, usually sufficient for full psychedelic effects including perceptual changes and introspection.

• The term "heroic dose" generally refers to much larger amounts, around 50 mg of psilocybin, which equates to approximately 5 grams of dried magic mushrooms assuming a typical psilocybin content of 1% by weight.

It’s important to note that in non-clinical settings (e.g., recreational use), the dosages can greatly vary due to differences in the psilocybin content of various mushroom strains and differences in individual tolerance or desired effect.

Lastly, when considering dosages, it's vital to remember that psilocybin remains a controlled substance in many parts of the world, and dosage should be handled with care under appropriate supervision in authorized therapeutic or research settings[1 2 3].