• What is tirzepitide

  • Sources:

    Tirzepatide, also known by the brand name Mounjaro, is a dual agonist peptide that targets both GLP-1 and GIP receptors. This medication is particularly noted for its efficacy in weight loss and management of type 2 diabetes. It is shown to be more effective in fat and weight loss compared to traditional weight loss drugs and GLP-1 agonists, such as semaglutide (brand names Ozempic and Wegovy) 1 2.

    Key Points:

    • Mechanism: Tirzepatide combines GLP-1 and GIP agonist actions, helping to regulate insulin and glucagon secretion, which improves metabolic health and may also positively affect skeletal muscle 3.
    • Administration: It is usually administered as a once-a-week injection, making it convenient for users who prefer fewer injections 2.
    • Effects: Apart from significant weight loss, tirzepitide has shown promising results in reducing appetite and potentially enhancing muscle protein synthesis, muscle sparing, and improving blood flow and stamina with microdoses 3 4.
    • Side Effects: While generally better tolerated than some previous weight loss medications, it can cause a reduction in appetite to the point where users need to ensure they still consume enough nutrients to avoid muscle loss 3.

    This multifaceted approach of tirzepitide showcases its potential beyond just weight loss, possibly impacting muscle health and overall metabolic functions.

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