Turmeric
Sources:
Turmeric, specifically its active compound curcumin, offers several health benefits but also poses some cautions particularly related to hormonal pathways. Here are some key points covered by Andrew Huberman:
-
Anti-inflammatory Properties: Curcumin, a component of turmeric, has potent anti-inflammatory effects. It can be effective in treating migraines by inhibiting nitric oxide synthesis, which reduces intracranial pressure and headache sensation. However, excessive intake might inhibit the natural inflammatory responses needed for physical training adaptations 1.
-
Interaction with Hormonal Pathways: Curcumin can significantly affect hormonal pathways, specifically by inhibiting the production of dihydrotestosterone (DHT). DHT is involved in many bodily functions such as libido and hair growth. High sensitivity to curcumin can lead to reduced DHT levels, potentially decreasing libido 1 2.
-
Dosage Considerations and Safety: The effective dose of curcumin can vary, with some studies using doses as low as 80 mg, often combined with omega-3 fatty acids to treat migraines. It's important to consider potential interactions with medications, especially anticoagulants, as curcumin can inhibit certain enzymes like cytochrome P450 which are involved in drug metabolism 1.
-
Potential Side Effects on DHT Levels: Curcumin's impact on DHT can be significant, especially for those who are sensitive. It acts as a DHT antagonist, and depending on individual sensitivity, this can affect hair growth on the scalp and other DHT-related bodily functions 3.
While turmeric is generally beneficial for its anti-inflammatory properties, its impact on hormonal levels means that individuals, especially those sensitive to hormone fluctuations, should use it cautiously and discuss it with a healthcare provider before starting supplementation.
RELATED QUESTIONS-
