does gaba pass the blood brain barrier?
Sources:
GABA (gamma-aminobutyric acid) generally does not pass the blood-brain barrier due to its molecular size. However, some formulations, like nicotinel GABA (GABA attached to vitamin B3), can cross the barrier because the B3 leads the way, allowing GABA to enter the brain 1 2.
Moreover, some people may report feeling effects from GABA supplements, possibly indicating a compromised blood-brain barrier (leaky brain) in those individuals 1 3.
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