What is cumulative pregnancy rate?

The cumulative pregnancy rate refers to the probability of achieving pregnancy after multiple attempts over a certain period of time. As explained by Andrew Huberman, it is based on the multiple probabilities associated with the chances of fertilization occurring, which involves both the egg and the sperm meeting successfully.

For example, for women under 30, the probability of conceiving in a single month is approximately 20%. Therefore, if conception does not occur in the first month, it is generally advised to try for about five to six months (since 20% probability multiplied by 5-6 months approaches 100%) before consulting an OB/GYN for potential fertility issues 1.

The probabilities change with age. For women aged 31-33, the success rate per month is about 18%, extending the recommended trial period naturally to six or seven months. For those aged 34-37, the probability is around 11% per month, suggesting a longer attempt period of about nine months to a year. Post-38 years, the probability drops significantly, leading to an increased emphasis on seeking medical advice earlier in the process 2.