Bupropion

Bupropion, known commercially as Wellbutrin, is primarily used for smoking cessation and as an antidepressant. It enhances the release of dopamine and, to a lesser extent, epinephrine and other neurochemicals. This action helps alleviate withdrawal symptoms from quitting smoking or vaping. The typical administration of Bupropion is 300 mg per day in two doses of 150 mg each, including a slow-release form. However, the dosage can vary based on individual factors.

It is important to note that Bupropion can increase the risk of seizures in a small fraction of the population, and its use should be monitored in patients with liver or renal disease. Interactions with other medications such as benzodiazepines can pose contraindications. Bupropion is not a universal solution for quitting smoking and should be prescribed by a qualified healthcare provider after considering all health aspects and potential interactions. The success rate for quitting smoking using Bupropion can increase from 5% to around 20% 1.